Bovine Glutamate Dehydrogenase 1, Mitochondrial, GLUD1 ELISA Kit , 96T Low-speed Centrifuges disease:A chromosomal aberration involving FOXO4

disease:A chromosomal aberration involving FOXO4 is found in acute leukemias

Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme

and possesses kinase activity

Three transcript variants encoding two different isoforms have been found for this gene

Bovine Glutamate Dehydrogenase 1, Mitochondrial, GLUD1 ELISA Kit , 96T Low-speed Centrifuges disease:A chromosomal aberration involving FOXO4Mitochondrial glutamate dehydrogenase that converts L glutamate into alpha ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed: 4365183, PubMed: 14659072). Plays a role in insulin homeostasis (By similarity). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).