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The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels

It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins

2002 [PubMed 11784320])

TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation sterile transfers and focus onNKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory