ANO10 Polyclonal Antibody, 100ul Centrifugal Filter Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented

this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras/MAP kinase

The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells

ANO10 Polyclonal Antibody, 100ul Centrifugal Filter Alternatively spliced transcript variants encodingThe transmembrane protein encoded by this gene is a member of a family of calcium activated chloride channels. Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia 10. Several transcript variants encoding different isoforms have been found for this gene.