F8I2 Rabbit Polyclonal Antibody, 100ul Serum Northern blotting studies have shown

Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons

Actin and other cytoskeletal proteins act as binding partners for the encoded protein

F8I2 Rabbit Polyclonal Antibody, 100ul Serum Northern blotting studies have shownThis gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h) containing F8A is repeated twice extragenically closer to the Xq telomere. Although its function is unknown the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII this gene is transcribed abundantly in a wide variety