MDR3 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene are

Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D

which bind to one another in a homophilic manner

Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and ligand-dependent nuclear receptor transcription coactivator activity

Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified

MDR3 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene areThe membrane associated protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR TAP subfamily. Members of the MDR TAP subfamily are involved in multidrug resistance as well as antigen