NPL4 Polyclonal Antibody, 50ul Cell Culture & Maintenance a rare salt wasting disease

a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids

The encoded protein may play an antioxidant protective role in cells| and may contribute to the antiviral activity of CD8(+) T-cells

it does not associate with beta-2-microglobulin or bind peptides

|online information:Interleukin-17 entry|PTM:Found both in glycosylated and nonglycosylated forms

NPL4 Polyclonal Antibody, 50ul Cell Culture & Maintenance a rare salt wasting diseaseBinds ubiquitinated proteins via its RanBP2 type zinc finger.,The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4 UFD1L VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.,pathway: Protein degradation;