Rsk-1/2/3/4 Polyclonal Antibody, 50ul[BT-AP08035] Monoclonal Antibodies Defects in RB1 are a

Defects in RB1 are a cause of childhood cancer retinoblastoma (RB)

a circulating inhibitor of the formation of new blood vessels (angiogenesis)

and it may play a role in membrane transport and signal transduction

The encoded protein is the receptor for sonic hedgehog

Rsk-1/2/3/4 Polyclonal Antibody, 50ul[BT-AP08035] Monoclonal Antibodies Defects in RB1 are aRPS6KA1 (ribosomal protein S6 kinase A1) encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding