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MSH2 Polyclonal Antibody, 100ul Vortex Mixer The protein encoded by this

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MSH2 Polyclonal Antibody, 100ul Vortex Mixer The protein encoded by thisMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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Description

The protein encoded by this gene is involved in processes including neurite growth and migration

Their voltage dependence is regulated by the concentration of extracellular potassium

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients

The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex

MSH2 Polyclonal Antibody, 100ul Vortex Mixer The protein encoded by thisMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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