Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs May act as a major

May act as a major enzyme for all-trans retinoic acid biosynthesis in extrahepatic tissues

PubMed: 2$458

This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor B

Interacts directly with BNIP1/SEC20L and ZW10

Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs May act as a majorInhibits the activity of dimeric NF kappa B REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (By similarity).