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Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis Three transcript variants encoding two

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Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis Three transcript variants encoding twoMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

Three transcript variants encoding two different proteins have been found for CSNK2A1

SYK and LAT via its SH2 domain

RAB3GAP2 has the highest level of expression in the brain

The enzyme requires NAD(H) as a coenzyme| and is inhibited by inorganic phosphate

Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis Three transcript variants encoding twoMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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