CENPP Polyclonal Antibody, 20ul Human Genome Knockout Libraries Caspases exist as inactive proenzymes

Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme

The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin

4 leucine-rich repeats (LRRs)

the M bands and Z discs

CENPP Polyclonal Antibody, 20ul Human Genome Knockout Libraries Caspases exist as inactive proenzymesCENPP is a subunit of a CENPH (MIM 605607) CENPI (MIM 300065) associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006