PPME1 Polyclonal Antibody, 100ul Biomatrix Expansion of a 20 amino

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

tissue specificity:Overexpressed in psoriasis

A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta

It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer

PPME1 Polyclonal Antibody, 100ul Biomatrix Expansion of a 20 aminoThis gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase 2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.