DDR1 Polyclonal Antibody, 100ul[BT-AP02534] Peptide Synthesis The gene is deleted in

The gene is deleted in Williams-Beuren syndrome| a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11

Mutations in this gene may contribute to autism susceptibility

this protein can bind BRCA1

and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in the absence of DNA damage

DDR1 Polyclonal Antibody, 100ul[BT-AP02534] Peptide Synthesis The gene is deleted inReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by DDR1 (discoidin domain receptor tyrosine kinase 1) belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of