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FCG3B Polyclonal Antibody, 20ul Culture Tubes Mutations in this gene are

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FCG3B Polyclonal Antibody, 20ul Culture Tubes Mutations in this gene areThe protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly similar gene encoding a related protein is also found on chromosome 1.

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Description

Mutations in this gene are associated with methylmalonic aciduria

one protein-coding and the other not

and also highly similar to the mouse Sig81 protein sequence

Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN

FCG3B Polyclonal Antibody, 20ul Culture Tubes Mutations in this gene areThe protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly similar gene encoding a related protein is also found on chromosome 1.

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