PTP22 Polyclonal Antibody, 20ul Live Cell Imaging Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants of this gene have been reported

diazepam and some barbiturates

This PTP also suppresses JAK kinases

This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

PTP22 Polyclonal Antibody, 20ul Live Cell Imaging Multiple alternatively spliced transcript variantsPTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1