Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix Histone deacetylase 4 encoded by

Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family

and mutations in that gene can abolish interaction with negative regulator of ubiquitin like proteins 1

Among its related pathways are Golgi-to-ER retrograde transport and Factors involved in megakaryocyte development and platelet production

Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement

Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix Histone deacetylase 4 encoded byThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.