Mdm2 Polyclonal Antibody, 50ul[BT-AP05302] Peptide Synthesis This gene encodes a protein

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold

MIM 613213) (Zhu et al

The encoded protein can also modulate signaling of other melanocortin receptors

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

Mdm2 Polyclonal Antibody, 50ul[BT-AP05302] Peptide Synthesis This gene encodes a proteinMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript