AMPK alpha2 Polyclonal Antibody, 100ul Immunoassays a rare and lethal autosomal

a rare and lethal autosomal recessive disorder of early childhood

Activity of the enzyme seems to be attenuated by autophosphorylation

Three transcript variants encoding two distinct isoforms have been identified for this gene

The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription

AMPK alpha2 Polyclonal Antibody, 100ul Immunoassays a rare and lethal autosomalThe protein encoded by this gene is a catalytic subunit of the AMP activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non catalytic beta and gamma subunits. AMPK is an important energy sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl CoA carboxylase (ACC) and beta hydroxy beta