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SHIP-1 Polyclonal Antibody, 50ul[BT-AP08295] Low retention tips It functions as a co-factor

SKU: 30369058749

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SHIP-1 Polyclonal Antibody, 50ul[BT-AP08295] Low retention tips It functions as a co-factorINPP5D is a member of the inositol polyphosphate 5 phosphatase (INPP5) family and encodes inositol polyphosphate 5 phosphatase D with an N terminal SH2 domain, an inositol phosphatase domain, and two C terminal protein interaction domains. Expression of inositol polyphosphate 5 phosphatase D is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane,

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Description

It functions as a co-factor of the DNA-bound androgen receptor complex

and its 3' end overlaps with that of the latter

The protein binds two cofactors

BNIP3 is silenced in tumors by DNA methylation

SHIP-1 Polyclonal Antibody, 50ul[BT-AP08295] Low retention tips It functions as a co-factorINPP5D is a member of the inositol polyphosphate 5 phosphatase (INPP5) family and encodes inositol polyphosphate 5 phosphatase D with an N terminal SH2 domain, an inositol phosphatase domain, and two C terminal protein interaction domains. Expression of inositol polyphosphate 5 phosphatase D is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane,

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