NU133 Polyclonal Antibody, 100ul DNA Oligo Synthesis A pseudogene of this gene

A pseudogene of this gene is found on chromosome 16

In contrast to human| the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

Increased expression of this gene is associated with some cases of leukemia

NU133 Polyclonal Antibody, 100ul DNA Oligo Synthesis A pseudogene of this geneThe nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by