p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development The encoded nuclear protein is

The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression

this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development

Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4

CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development The encoded nuclear protein isTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.