TRPM8 Polyclonal Antibody, 100ul Mechanical Pipette A pseudogene of this gene

A pseudogene of this gene is located on chromosome 12

The human genome contains many pseudogenes similar to this locus

which becomes hyperphosphorylated in cell cycle M phase

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm

TRPM8 Polyclonal Antibody, 100ul Mechanical Pipette A pseudogene of this geneReceptor activated non selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage dependent gating. Activated upon