Sclerostin Polyclonal Antibody, 20ul Liquid Storage Consumables Members of the FOX family

Members of the FOX family of transcription factors are regulators of embryogenesis and may play a role in human cancer

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

as well as fertility

and it may also mediate both cell proliferation and cell death

Sclerostin Polyclonal Antibody, 20ul Liquid Storage Consumables Members of the FOX familySclerostin (SOST) is a secreted glycoprotein with a C terminal cysteine knot like (CTCK) domain and sequence similarity to the DAN (differential screening selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss of function mutations in SOST are associated with an autosomal recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced