PEA-15(Phospho Ser116) Polyclonal Antibody, 100ul Cell Labeling & Imaging whose members play a key

whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors

Regulates signaling cascades probably through protein ubiquitination and/or sequestration

cofactor:Binds 2 zinc ions per subunit

The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK

PEA-15(Phospho Ser116) Polyclonal Antibody, 100ul Cell Labeling & Imaging whose members play a keyThis gene encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.