HMG-1 Polyclonal Antibody, 20ul[BT-AP04142] Bacterial Expression and studies in mice show

and studies in mice show that overexpression of GSK3B may be relevant to the pathogenesis of Alzheimer disease

This protein also acts as a metastasis suppressor

is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis

then this is known to affect dendritic spine morphology and formation---this is thought to occur through the Rac1/PAK1/LIMK/CFL1 pathway

HMG-1 Polyclonal Antibody, 20ul[BT-AP04142] Bacterial Expression and studies in mice showHMGB1 encodes high mobility group protein B1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript