LIMK-1/2 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis a leukocyte-specific adaptor protein important

a leukocyte-specific adaptor protein important for immune cell signaling

The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface

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LIMK-1/2 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis a leukocyte-specific adaptor protein importantThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase