SRPK2 Polyclonal Antibody, 100ul Liquid Handling ＆Storage This gene is a homolog

This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene

Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10

The protein is also involved in cell growth and differentiation

a kidney disorder involving both tubules and glomeruli

SRPK2 Polyclonal Antibody, 100ul Liquid Handling ＆Storage This gene is a homologCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Ser 52 and Ser 588.,Phosphorylates RS domain containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral