p21 Polyclonal Antibody, 20ul[BT-AP12603] Roller Bottles Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different proteins have been identified

Mice deficient for this gene have increased fat mass despite decreased food intake

This protein is localized to the trans Golgi network

Cytochrome P450 2A7 localizes to the endoplasmic reticulum

p21 Polyclonal Antibody, 20ul[BT-AP12603] Roller Bottles Alternatively spliced transcript variants encodingThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of