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GPS2 Polyclonal Antibody, 100ul Centrifugal Filter CD160 is expressed at the

SKU: 28389572790

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USD141.00 USD165.00

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GPS2 Polyclonal Antibody, 100ul Centrifugal Filter CD160 is expressed at theGPS2 encodes G protein pathway suppressor 2 involved in G protein mitogen activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS and MAPK mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1 HDAC3 (nuclear receptor corepressor 1 histone deacetylase 3)

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Description

CD160 is expressed at the cell surface as a tightly disulfide-linked multimer

Expression is slightly down-regulated by dexamethasone and slightly up-regulated by IL-10

This protein binds specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly

and these opposite actions are thought to be mediated by two classes of receptors

GPS2 Polyclonal Antibody, 100ul Centrifugal Filter CD160 is expressed at theGPS2 encodes G protein pathway suppressor 2 involved in G protein mitogen activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS and MAPK mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1 HDAC3 (nuclear receptor corepressor 1 histone deacetylase 3)

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