MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases Mutations in CSH1 result in

Mutations in CSH1 result in placental lactogen deficiency and Silver-Russell syndrome

and the polyA addition motif

for this protein

The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences

MYLK Polyclonal Antibody, 100ul[BT-AP05707] Endonucleases & Exonucleases Mutations in CSH1 result inMYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein