SENP3 Polyclonal Antibody, 20ul Thermal Control In neck and head squamous

In neck and head squamous cell carcinomas

MRGPRX3 encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors

Mitogen-activated protein kinase 8 localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways

The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

SENP3 Polyclonal Antibody, 20ul Thermal Control In neck and head squamousThe reversible posttranslational modification of proteins by the addition of small ubiquitin like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO