Pax-2 Polyclonal Antibody, 50ul In vitro Transcription The encoded protein functions as
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Pax-2 Polyclonal Antibody, 50ul In vitro Transcription The encoded protein functions asPAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of PAX2 results in multiple
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