KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation This cytokine is also found

This cytokine is also found to promote proliferation and migration of endothelial cells

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

Gene expression is high during fetal development and in most tumors

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation This cytokine is also foundThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia