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HXD11 Polyclonal Antibody, 20ul Cryopreservation Several transcripts encoding different isoforms

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HXD11 Polyclonal Antibody, 20ul Cryopreservation Several transcripts encoding different isoformsThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2.

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Description

Several transcripts encoding different isoforms have been found for this gene

Component of the NF-kappa-B p65-p52 complex

Binding of its ligand| hepatocyte growth factor| induces dimerization and activation of the receptor| which plays a role in cellular survival| embryogenesis| and cellular migration and invasion

Leber hereditary optic neuropathy

HXD11 Polyclonal Antibody, 20ul Cryopreservation Several transcripts encoding different isoformsThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2.

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