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NEIL1 Polyclonal Antibody, 100ul Microplate Mixer The protein encoded by this

SKU: 27313451070

4.4
PLN141.00 PLN164.00

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NEIL1 Polyclonal Antibody, 100ul Microplate Mixer The protein encoded by thisNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

The protein encoded by this gene belongs to the SECY/SEC61- alpha family

Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease

Alternative splicing

Inhibition of the encoded protein restores hemostasis in animal models of hemophilia

NEIL1 Polyclonal Antibody, 100ul Microplate Mixer The protein encoded by thisNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

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