Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis Component of the SCF(SKP2) complex
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Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis Component of the SCF(SKP2) complexSerine kinase that plays an essential role in the NF kappa B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF kappa B activation and phosphorylates inhibitors of NF kappa B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and
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