Histone H3 Polyclonal Antibody, 50ul[BT-AP10030] Multiplex Immunoassays Covalent attachment to its substrates

Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M

and unlike most DEAD-box helicases

The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product| which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast

Rab proteins are small GTPases that are involved in vesicular trafficking

Histone H3 Polyclonal Antibody, 50ul[BT-AP10030] Multiplex Immunoassays Covalent attachment to its substratesHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin