ZNRF1 Polyclonal Antibody, 20ul Bio-Reaction Tube Mice that do not express

Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

subcellular location:Colocalizes with endosomes

belongs to the POTE family

Probable metal transporter

ZNRF1 Polyclonal Antibody, 20ul Bio-Reaction Tube Mice that do not expressThis gene encodes an E3 ubiquitin protein ligase that plays a role in neural cell differentiation. Overexpression of this gene causes neurite like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome lysosome compartment, indicating that it may be involved in ubiquitin mediated protein modification, and in synaptic vessicle membranes in neurons.