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Luciferase mouse Monoclonal Antibody(6B8), 50ul Capsule Filter Binding of this protein destabilizes

SKU: 2610487470

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Luciferase mouse Monoclonal Antibody(6B8), 50ul Capsule Filter Binding of this protein destabilizesLuciferase from the firefly has become one of the more widely used reporter proteins for the study of gene expression. Luciferase catalyzes a bioluminescent reaction which requires the substrate luciferin as well as Mg2+ and ATP. Mixing these reagents with the cell extract containing luciferase, results in a flash of light that decays rapidly. This light can be detected by a luminometer. The total light emission is proportional to the luciferase

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Description

Binding of this protein destabilizes the neuronal nitric oxide synthase dimer| a conformation necessary for activity| and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity

Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH)

and has been shown to regulate the helicase activity of the complex

Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

Luciferase mouse Monoclonal Antibody(6B8), 50ul Capsule Filter Binding of this protein destabilizesLuciferase from the firefly has become one of the more widely used reporter proteins for the study of gene expression. Luciferase catalyzes a bioluminescent reaction which requires the substrate luciferin as well as Mg2+ and ATP. Mixing these reagents with the cell extract containing luciferase, results in a flash of light that decays rapidly. This light can be detected by a luminometer. The total light emission is proportional to the luciferase

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