SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification and a C-terminal chromo shadow-domain
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SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification and a C-terminal chromo shadow-domainThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in
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