IKK gamma Polyclonal Antibody, 100ul[BT-AP02164] Cell Function Analysis The MAPKKK5 protein phosphorylates and

The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1| MAPKK4) in vitro| and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells

It also may be involved in the assembly of the B

Prostaglandin E synthase encoded by PTGES is a glutathione-dependent prostaglandin E synthase

but the full-length nature of these variants has not been determined

IKK gamma Polyclonal Antibody, 100ul[BT-AP02164] Cell Function Analysis The MAPKKK5 protein phosphorylates andThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.