Raf-B Polyclonal Antibody, 100ul[BT-AP07630] Cell Senescence online information:Siglec-9

online information:Siglec-9

Mutations in this gene and a highly similar gene located nearby

Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress

Polymorphisms in this gene have been linked to breast and prostate cancer

Raf-B Polyclonal Antibody, 100ul[BT-AP07630] Cell Senescence online information:Siglec-9BRAF (B Raf proto oncogene, serine threonine kinase) encodes a protein belonging to the raf mil family of serine threonine protein kinases. This protein plays a role in regulating the MAP kinase ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.