GCM1 Rabbit Polyclonal Antibody, 50ul Metabolic enzymes tool compounds Increased expression of ABCC12 is

Increased expression of ABCC12 is associated with breast cancer

This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion

GO annotations related to this gene include RNA binding and RNA-3-phosphate cyclase activity

Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome

GCM1 Rabbit Polyclonal Antibody, 50ul Metabolic enzymes tool compounds Increased expression of ABCC12 isThis gene encodes a DNA binding protein with a gcm motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM motif (A G)CCCGCAT a novel sequence among known targets of DNA binding proteins. The N terminal DNA binding domain confers the unique DNA binding activity of this protein.