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Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development A pseudogene for this gene

SKU: 24919158642

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Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development A pseudogene for this geneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

A pseudogene for this gene is located on chromosome 11q13

which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2

9 PCR Tube Adapter

which is composed of eight protein subunits and highly conserved in eukaryotic cells

Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development A pseudogene for this geneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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