NPRL2 Polyclonal Antibody, 50ul Cell Dissociation similarity:Contains 6 Kelch repeats

similarity:Contains 6 Kelch repeats

cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands

This protein binds to all three of the tumor suppressor proteins pRB

GO annotations related to this gene include calcium ion binding and protein heterodimerization activity

NPRL2 Polyclonal Antibody, 50ul Cell Dissociation similarity:Contains 6 Kelch repeatsSuppresses Src dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr 9 Tyr 373 and Tyr 376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.