ITA11 Polyclonal Antibody, 20ul Cryogenic Vials Mutations in the coding region

Mutations in the coding region of this gene are associated with Bruck syndrome

This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

This encoded protein is a cell surface glycoprotein that is known to complex with integrins

ITA11 Polyclonal Antibody, 20ul Cryogenic Vials Mutations in the coding regionThis gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this