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p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences T-cell acute lymphoblastic leukemia

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p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences T-cell acute lymphoblastic leukemiaTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

T-cell acute lymphoblastic leukemia

Numerous pseudogenes have been reported for this gene

Mutations in this gene are associated with erythrocytosis familial type 4

including nuclear transport

p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences T-cell acute lymphoblastic leukemiaTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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