GPSM2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management The protein encoded by CELSR1

The protein encoded by CELSR1 (cadherin EGF LAG seven-pass G-type receptor 1) is a member of the flamingo subfamily

and the reproductive tracts

Mutations in this gene result in one form of autosomal dominant hearing impairment

The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains

GPSM2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management The protein encoded by CELSR1The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N terminal half of this protein contains 10 copies of leu gly asn (LGN) repeat, and the C terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and