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TP53INP2 Polyclonal Antibody, 100ul[BT-AP09142] Sealing Film The protein localizes to lysosomes

SKU: 24166399212

4.4
SEK123.75 SEK145.75

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TP53INP2 Polyclonal Antibody, 100ul[BT-AP09142] Sealing Film The protein localizes to lysosomesThe protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.

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Description

The protein localizes to lysosomes and the Golgi apparatus

which shows substantial homology to Ca2+/calmodulin-dependent protein kinase

namely HM74A and HM74B (also known as simply HM74)

An important paralog of this gene is IQGAP1

TP53INP2 Polyclonal Antibody, 100ul[BT-AP09142] Sealing Film The protein localizes to lysosomesThe protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.

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