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Gab 2(Phospho Ser159) Polyclonal Antibody, 100ul Polyclonal Antibodies and to a lesser degree

SKU: 23693730250

4.1
USD108.00 USD129.00

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Gab 2(Phospho Ser159) Polyclonal Antibody, 100ul Polyclonal Antibodies and to a lesser degreeThis gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in

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Description

and to a lesser degree

Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP

The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha)

with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs

Gab 2(Phospho Ser159) Polyclonal Antibody, 100ul Polyclonal Antibodies and to a lesser degreeThis gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in

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